Change predictive according to Gig File size?

Sure, sorry. You can use Gig Performer multiple times (even at the same time) without the individual instances knowing from each other or interfering with one another.
That means separate processor cores but also individual setting files which can be beneficial in your case: one instance can have predictive loading set to 3, the other one set to a different number.
You would open your regular gig files in the normal instance and the big one in the latter.

I think this is a good collection of knowledge about this even though it’s still called Gig Performer 4:

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