If you want to quickly start GP without it reloading the last gig file (if that option is enabled) - simply hold down the SHIFT key while opening GP and it will not load your last gig.
The tip above applies to Gig Performer 3 and older editions.
How is it in Gig Performer 4, learn in this (latest) blog article: Gig Performer | What are Temporary Startup Options in Gig Performer?
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