I also use an Ui24R in band-context. I’ve learned from some other communities, and by own experience, that the Ui24R USB audio interface and the internal power supply for USB is designed quite poor.
I also had USB failures in the beginnig, because of mains issues (switching on/off power of the rehearsal room fridge, guitar amps, neon lights etc.) and some grounding issues (e.g. plugging active speaker wedges while running…)
What I did was inserting an USB isolator (https://www.amazon.de/gp/product/B0BTVL6J4M) and a UPS on mains (https://www.amazon.de/dp/B07KZ9LTFZ)
No more problems since then!