Any news on this? I just tried Matrix Coconut. I noticed using it for 1 ASIO device it didn’t seem to add any latency, and was quite happy with how it worked. I haven’t tried combining multiple interfaces yet. However, I did try using VBAN to send audio to another computer on my network. I’ve been dreaming of a near zero way to send audio between computers on my network, similar to how Dante works. I found that VBAN itself definitely adds some latency, but by changing the buffer size to 64 samples on both computers, it was almost acceptable for realtime use. However, as you mentioned this requires a powerful computer to run at such low buffer sizes.
Do you happen to know where in the User Interface the "Performance Mode’ settings are?