you did not activate your GP yet so it may cut the sound from time to time, but you would notice this as the screen would go red and a message would be displayed telling you what happened.
Some of your plugins are not activated and they are cutting the sound.
Other than that - if things worked fine before - something changed on your system. Maybe a plugin lost a previously good activation and needs to be reactivated?
If you bypass all the plugins - does it happen then. your guitar sound will just go out through the interface, but we’ll know if the problem is with one of the plugins.
If that works - you can then enable them one by one and maybe figure out which one is causing the problems…