Here’s the solution I came up with works great for me, everything pretty much stays connected for quick and easy setup. I picked up a Roland RRC-DJ808W Black Series DJ Road Case from Musician’s Friend as a Stupid Deal of the Day for $99.
I created a padded space under the platform to stow the laptop I just roll up the cables (mic,guitar, foh) and put the lid on. There is a powered USB hub under the laptop. Everything is held in place with tie straps and Velcro. The only thing I unplug is the USB cables to the laptop. The only downside is it is kind of heavy!