I updated my 2016 MacBook Pro to the new, Monterey OS and I’m happy to report no problems with Gig Performer so far. All my plugins are AUs. They include S-Gear, Kontakt, EZdrummer, various Waves effects, and one or two additional items. I needed to provide my license info again, just as I did when I went to Big Sur.
Note that I’m in development mode, rather than performing, so I could take the risk. In addition, I will receive a new M1 Pro machine in a couple of weeks, which ships with Monterey, and I wanted to test the water.
Living life on the edge.