Solved the problem. In Win10 you can use only one midi controller per instance. I found another thread here were this problem was already in discussion. The solution is to use the free program loopBe1. In the second instance you set this virtual midi controller as the midi controller. So you send midi messages from the first instance to the second. Now I can set even the global settings in the second instance. I thougt it does not work, but I figured out, that you have to clear the settings of the first instance which are routed to the midi controller. And you have to create a midi in in the first instance and route it to the midi out with the loopbe1.
Thanks for advise. Maybe someone else have the same problem with win10. Good night!!!