Asio multi-client is hardly ever mentioned and it is difficult to get this information.
You are right: just try loading a 2nd instance and you will know immediately.
I have the info from the Native support. So yes, simply try it. 
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I am such a beginner with MacOS…
I forgot that ASIO is windows territory.
It seems that all core audio driver in MacOS are multi client.
Is it true? I am playing with a new M1 based MacBook Pro.
Today I had to play hours with Logic Pro and I forgot to test double instance with my board.
If this is true I can plan future board purchasing with calm
Yes, on Mac you have less problems 
Yes, it’s true.